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Charles Antzelevitch Selected Research

Ranolazine

10/2016Ranolazine for Congenital Long-QT Syndrome Type III: Experimental and Long-Term Clinical Data.
7/2014Ranolazine effectively suppresses atrial fibrillation in the setting of heart failure.
1/2012Atrial-selective sodium channel block strategy to suppress atrial fibrillation: ranolazine versus propafenone.
11/2011Ranolazine versus amiodarone for prevention of postoperative atrial fibrillation.
8/2011Electrophysiologic basis for the antiarrhythmic actions of ranolazine.
10/2010Synergistic effect of the combination of ranolazine and dronedarone to suppress atrial fibrillation.
2/2010Synergistic electrophysiologic and antiarrhythmic effects of the combination of ranolazine and chronic amiodarone in canine atria.
5/2008Ranolazine: a new antiarrhythmic agent for patients with non-ST-segment elevation acute coronary syndromes?
9/2007Atrium-selective sodium channel block as a strategy for suppression of atrial fibrillation: differences in sodium channel inactivation between atria and ventricles and the role of ranolazine.
5/2007Cellular basis for the electrocardiographic and arrhythmic manifestations of Timothy syndrome: effects of ranolazine.
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Charles Antzelevitch Research Topics

Disease

50Brugada Syndrome
05/2022 - 02/2002
29Atrial Fibrillation
01/2020 - 09/2007
27Cardiac Arrhythmias (Arrythmia)
01/2022 - 01/2004
18Ventricular Tachycardia
01/2018 - 08/2004
15Torsades de Pointes (Torsade de Pointes)
12/2021 - 02/2003
14Long QT Syndrome
01/2018 - 02/2002
11Cardiac Sudden Death (Sudden Cardiac Arrest)
01/2020 - 02/2006
10Heart Failure
07/2014 - 02/2003
7Ventricular Fibrillation
01/2018 - 04/2002
6Channelopathies
12/2021 - 08/2004
5Timothy syndrome
12/2016 - 05/2007
5Premature Cardiac Complexes (Extrasystoles)
11/2013 - 01/2003
5Ischemia
12/2011 - 10/2005
4Heart Arrest (Cardiac Arrest)
06/2018 - 05/2005
4Bradycardia
10/2016 - 02/2006
4Tachycardia (Tachyarrhythmias)
10/2011 - 02/2006
4Short Qt Syndrome
05/2011 - 04/2004
3Polymorphic catecholergic ventricular tachycardia
01/2022 - 05/2005
3Heart Diseases (Heart Disease)
01/2020 - 01/2008
3Sudden Infant Death (SID)
01/2018 - 04/2010
3Sudden Death
04/2012 - 10/2005
3Hyperkalemia
02/2006 - 02/2005
2Disease Susceptibility (Diathesis)
05/2022 - 01/2022
2Migraine Disorders (Migraine)
12/2020 - 07/2015
2Hypothermia
01/2020 - 02/2014
2Fever (Fevers)
06/2018 - 01/2016
2Ventricular Premature Complexes (Premature Ventricular Contraction)
01/2017 - 02/2010
2Syncope (Fainting)
02/2016 - 02/2010
2Rhabdomyolysis
01/2014 - 02/2006
2Genetic Predisposition to Disease (Genetic Predisposition)
07/2013 - 04/2012
2Inflammation (Inflammations)
01/2012 - 07/2009
2Acute Coronary Syndrome
08/2011 - 05/2008
2Andersen Syndrome
02/2011 - 03/2006
2Cardiomyopathies (Cardiomyopathy)
09/2007 - 04/2006
2Hypercalcemia (Milk Alkali Syndrome)
04/2005 - 02/2005
1Acute Pain
12/2021
1Irritable Bowel Syndrome (Syndrome, Irritable Bowel)
01/2021
1Spinocerebellar Ataxias (Spinocerebellar Ataxia)
07/2020
1Rare Diseases (Rare Disease)
01/2020
1Atrioventricular Nodal Reentry Tachycardia (AV Nodal Reentrant Tachycardia)
01/2018
1Sick Sinus Syndrome
01/2018
1Shock
02/2016

Drug/Important Bio-Agent (IBA)

30Sodium Channels (Sodium Channel)IBA
05/2022 - 02/2002
16Pharmaceutical PreparationsIBA
01/2021 - 12/2003
13RanolazineFDA Link
10/2016 - 08/2004
12Ion Channels (Ion Channel)IBA
12/2021 - 02/2002
11Quinidine (Chinidin)FDA LinkGeneric
12/2021 - 01/2005
9CalciumIBA
01/2020 - 05/2003
9SodiumIBA
01/2018 - 07/2004
8Calcium Channels (Calcium Channel)IBA
01/2016 - 07/2004
7Sodium Channel BlockersIBA
01/2020 - 01/2005
6PotassiumIBA
01/2022 - 05/2004
6Amiodarone (Amiodarona)FDA LinkGeneric
11/2011 - 01/2008
5Ajmaline (Wolfina)FDA Link
01/2020 - 01/2004
5Antidepressive Agents (Antidepressants)IBA
08/2018 - 02/2005
5Anti-Arrhythmia AgentsIBA
03/2008 - 04/2004
4Flecainide (Tambocor)FDA LinkGeneric
07/2020 - 04/2004
4Proteins (Proteins, Gene)FDA Link
01/2020 - 04/2008
41- (3,5- bis- trifluoromethylphenyl)- 3- (2,4- dibromo- 6- (1H- tetrazol- 5- yl)phenyl)ureaIBA
01/2020 - 03/2009
4wenxin keliIBA
03/2016 - 01/2012
4Isoproterenol (Isoprenaline)FDA LinkGeneric
01/2016 - 01/2005
4Acetylcholine (Acetylcholine Chloride)FDA Link
06/2012 - 09/2008
3Ryanodine Receptor Calcium Release Channel (Ryanodine Receptor)IBA
01/2022 - 05/2005
3L-Type Calcium Channels (Dihydropyridine Receptor)IBA
12/2016 - 01/2007
3Cilostazol (Pletal)FDA LinkGeneric
01/2016 - 11/2013
3Milrinone (Primacor)FDA LinkGeneric
01/2016 - 11/2013
3Terfenadine (Seldane)IBA
03/2006 - 01/2003
2Voltage-Gated Sodium ChannelsIBA
07/2020 - 01/2019
2Verapamil (Calan)FDA LinkGeneric
01/2020 - 03/2006
2Calcium Channel Blockers (Blockers, Calcium Channel)IBA
01/2020 - 05/2003
2Antipsychotic Agents (Antipsychotics)IBA
08/2018 - 03/2008
2Bepridil (Vascor)FDA Link
01/2017 - 01/2016
2Potassium Channels (Potassium Channel)IBA
04/2012 - 10/2005
2Sotalol (Sotalol Hydrochloride)FDA LinkGeneric
03/2012 - 04/2004
2Adenosine (Adenocard)FDA LinkGeneric
10/2011 - 02/2006
2Inwardly Rectifying Potassium Channels (Inward Rectifier Potassium Channels)IBA
02/2011 - 03/2006
2DronedaroneFDA Link
10/2010 - 09/2010
2Adenosine Triphosphate (ATP)IBA
10/2010 - 03/2006
2RyanodineIBA
05/2005 - 05/2003
2Adrenergic alpha-Agonists (Adrenergic alpha-Agonist)IBA
04/2005 - 02/2005
2Glucose (Dextrose)FDA LinkGeneric
04/2005 - 02/2005
2Adrenergic beta-Antagonists (beta-Adrenergic Blocking Agents)IBA
04/2005 - 02/2005
2Insulin (Novolin)FDA Link
04/2005 - 02/2005
2Cocaine (Cocaine HCl)IBA
04/2005 - 02/2005
1Carvedilol (Coreg)FDA LinkGeneric
01/2022
1Dantrolene (Dantrium)FDA LinkGeneric
01/2022
1Opioid Receptors (Opioid Receptor)IBA
12/2021
1((3- methoxythiophen- 2- yl)methyl)((2- (9- (pyridin- 2- yl)- 6- oxaspiro(4.5)decan- 9- yl)ethyl))amineIBA
12/2021
1LigandsIBA
12/2021
1Adenosine Monophosphate (AMP)IBA
01/2021
1(R)- N- (benzimidazol- 2- yl)- 1,2,3,4- tetrahydro- 1- naphthylamineIBA
01/2020
1Calcium-Activated Potassium Channels (Calcium-Activated Potassium Channel)IBA
01/2020

Therapy/Procedure

18Therapeutics
01/2020 - 02/2003
6Implantable Defibrillators (Implantable Cardioverter-Defibrillator)
02/2016 - 11/2002
3Radiofrequency Ablation
01/2018 - 01/2016
3Cardiac Resynchronization Therapy
12/2005 - 02/2003
2Defibrillators (Defibrillator)
06/2018 - 03/2006
2Anesthesia
11/2012 - 09/2006
2Transplantation
03/2012 - 04/2006
2Drug Therapy (Chemotherapy)
04/2008 - 04/2004